"At Salman Lab, we delve deep into the complexities of dementia and other neurodegenerative diseases by investigating one of the key players in disease progression—the blood-brain barrier (BBB)."
- Mootaz Salman
Research
Dynamic 3D BBB Models
We simulated blood-brain barrier and brain function under neurodegenerative conditions using 3D models.
Development of BBB-on-a-chip
We developed advanced microfluidic models to understand blood-brain barrier functions in real-time.
Neuroinflammation and the Glymphatic System
We investigated how neuroinflammation impacts the glymphatic system and brain waste clearance using patient-derived iPSC lines.
Therapeutic Targets for Dementia Prevention
We aimed to define and validate new therapeutic targets that could effectively prevent the onset of dementia. Our extensive research focused on identifying molecular pathways and cellular interactions critical to maintaining blood-brain barrier integrity and overall brain health.
